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Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

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Abstract Mutations in the Cockayne Syndrome group B (CSB) gene cause cancer in mice. but premature aging and severe neurodevelopmental defects in humans. CSB. a member of the SWI/SNF family of chromatin remodelers. https://www.roneverhart.com/Toshiba-AL13SX-AL13SXB30EN-300GB-15K-RPM-SAS-12Gb-s-512n-128MB-2-5-Hard-Drive/
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